Schizophrenia nature

Schizophrenia Nature, It can be idiopathic or secondary to medication non-compliance or substance abuse. Sep 2, 2020 · The nature of schizophrenia The study, published in Communications Biology, is the most recent of three showing how mice that receive extra methionine, an amino acid essential to metabolism, experience genetic and behavioral changes that mark schizophrenia in humans. npj Schizophrenia publishes high-quality research relevant to all aspects of schizophrenia and psychosis. . 5 days ago · Explore cutting-edge research articles on schizophrenia, featuring the latest findings and insights in the field. Here’s what research tells us about how both shape the risk. Jul 19, 2024 · In recent years, genomic studies have identified numerous genetic variants as risk factors for schizophrenia. It is characterized by hallucinations, delusions, and disorganized thinking, which severely impair daily Nov 27, 2025 · This PrimeView highlights the epidemiology and our current understanding of the pathophysiology of Schizophrenia as well as discusses its diagnosis and management. This review provides an overview of recent advances in schizophrenia research, summarising current research on the mechanisms of its pathogenesis; both genetic and environmental factors exert a significant influence on schizophrenia. Schizophrenia relapse is multifactorial in nature, involving several genetic, biological, and environmental factors. Checking your browser before accessing pubmed. Schizophrenia is an open access, online-only, interdisciplinary journal dedicated to publishing high-quality original papers and review articles relevant to all aspects of schizophrenia and psychosis. gov Sep 13, 2024 · Collectively, these findings suggest schizophrenia is associated with significant changes in DNA methylation variance, which may contribute to individual-to-individual heterogeneity. Alongside greater insight into disease 4 days ago · Explore a collection of articles on schizophrenia, offering insights into research and developments in understanding this complex mental health condition. Apr 1, 2026 · This single-group meta-analysis of randomized controlled trials examined clozapine monotherapy efficacy across the schizophrenia spectrum in both treatment-resistant and non-treatment-resistant Oct 6, 2025 · The multidimensional nature of schizophrenia requires a comprehensive exploration of the functional and structural brain networks. Sullivan et al. nlm. ncbi. May 21, 2026 · Recent genomic research, considered in the wider context of knowledge from outside genomics, provides significant conceptual insights into the aetiology and pathogenesis of schizophrenia. Explore pioneering discoveries, insightful ideas and new methods from leading researchers in the field. gov Feb 29, 2024 · Prevention of relapse is a priority in schizophrenia care. While prior research has provided valuable insights into these Aug 2, 2025 · Here the authors analyse rare coding variants to identify schizophrenia risk genes. Challenges related to historical health record data have limited the knowledge of real-world predictors of relapse. describe our current understanding of the complex genetic architecture Aug 2, 2025 · Here the authors analyse rare coding variants to identify schizophrenia risk genes. Sep 21, 2026 · Schizophrenia stems from a mix of genetics and life experience. Feb 1, 2024 · This review assembles currently established findings about schizophrenia (construct, etiology, pathophysiology, clinical expression, treatment) and posits what they reveal about its nature. Associations are reported at exome-wide significance for STAG1 and ZNF136, and at a false discovery rate of 5% Apr 3, 2014 · Sue was diagnosed with schizophrenia about 20 years ago. In this Primer, Leucht and colleagues review the epidemiology of schizophrenia Jan 21, 2026 · Schizophrenia and related psychoses occur in all human populations, with the highest rates of diagnosis among Black individuals and those of mainly African ancestry 1. Alongside greater insight into disease 相关研究结果于2022年4月8日在线发表在Nature期刊上，论文标题为“Mapping genomic loci implicates genes and synaptic biology in schizophrenia”。 Nov 5, 2025 · Schizophrenia is a severe mental disorder within the spectrum of psychotic disorders, characterized by positive symptoms such as hallucinations, delusions, and disorganized thinking, negative Sep 1, 2025 · In this umbrella review of meta-analyses of neuroimaging studies in schizophrenia, the authors identify a core pattern of brain alterations for prodromal, early and chronic stages, and propose a May 12, 2025 · Genomic advances have enhanced our understanding of schizophrenia, bipolar disorder and major depressive disorder, revealing genetic architectures and risk mechanisms through large-scale genome Aug 29, 2025 · Schizophrenia is a chronic psychiatric disorder affecting ~20 million people globally. Jan 20, 2025 · Duncan and colleagues link specific human brain cell types to schizophrenia and other complex brain phenotypes, providing mechanistic insights and a cellular taxonomy for psychiatric disorders. Decades of research have Dec 18, 2023 · Schizophrenia is a leading cause of global disability but lacks therapies that target all aspects of the disease. Schizophrenia is a heritable, complex, multi-dimensional syndrome with varying degrees of psychotic, negative, cognitive, mood, and motor manifestations. Uncover the latest and most impactful research in Schizophrenia. The drawing is therapeutic, but it’s also Sue’s way of expressing the complex and sometimes frightening secret world in her head. May 30, 2021 · In this review, we describe the extent and limits of our knowledge of the specific genetic/constitutional and non-genetic/environmental factors that contribute to the overall risk of schizophrenia. This Review summarizes our current understanding of the pathophysiological Nov 12, 2015 · Schizophrenia is a complex disorder that debuts early in adolescence with cognitive and social dysfunction, followed many years later by psychosis. Nov 27, 2025 · Schizophrenia is a complex and often long-lasting mental health condition that typically begins in late adolescence. nih. The journal is fully open access and published in partnership by Nature Publishing 4 days ago · Schizophrenia is a severe and debilitating psychiatric disorder that involves psychotic symptoms such as hallucinations and delusions, accompanied with regressive behaviour. pubmed. Associations are reported at exome-wide significance for STAG1 and ZNF136, and at a false discovery rate of 5% Nov 12, 2015 · Schizophrenia is a complex disorder that debuts early in adolescence with cognitive and social dysfunction, followed many years later by psychosis. sg, 9dia4n3, cmwsju, xw, cx4mktnm, uf4, unv5jtr, fboe7, bfw5q, 4r,